Licorice, distributed in Northeast China, North China, Shaanxi, Gansu, Qinghai, Xinjiang, Shandong and other places. It has the functions of tonifying spleen and qi, clearing heat and detoxifying, expectorating cough, relieving pain and reconciling various medicines. It is often used for spleen and stomach weakness, fatigue, palpitation, shortness of breath, cough and phlegm, epigastric abdomen, limb clonus pain, carbuncle, swelling and sores, relieve drug toxicity and intensity. Licorice fermentation water is the root of licorice and yeast fermentation, fermentation after the molecular weight is smaller, easier to be absorbed by the skin.